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10.1039/C9NR08747H 79 HuangT.HeJ

These modifications have been hypothesized to play a crucial role in the diffusion of DNA damage response/senescence-associated secretory phenotype (DDR/SAPS) signaling to non-damaged surrounding cells during aging, suggesting that DDR/SASP signaling components may contribute to the development of novel therapeutic interventions against age-related diseases (Olivieri et al., 2015)