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D., Miller, J

Caution is advised in patients with Leber optic atrophy, a genetic disorder caused by chronic cyanide intoxication (such as from smoking, alcohol or some plants), against the use of cyano-B12 due to its cyanide moiety, whilst hydroxo-B12 is a cyanide antagonist and can therefore be used in these patients

However, PRP has substantially more clinical evidence supporting its use and established safety profiles for numerous applications

Thats why medical oversight and lab testing are essential

Hematoxylin was used for counterstaining for 2 min, followed by differentiation with 1% hydrochloric acid solution