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17-estradiol differentially regulates blood-brain barrier permeability in young and aging female rats

doi:10.1016/j.eururo.2009.08.001

In this field, the main challenges are represented by data quality management, standardization of statistical models, and normalization methods across different pipelines and, ultimately, the biological interpretation and validation of findings

Furthermore, increased peroxynitrite may also contribute to cytokine-induced cardiac contractile failure by inactivating sarcoplasmic Ca 2+ -ATPase and disrupting Ca 2+ homeostasis [161]