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Although there is a broad clinical spectrum of glutathione synthetase deficiency, manifestations usually include hemolytic anemia, often include metabolic acidosis, and sometimes include progressive neurologic symptoms as well as other systemic signs (eg, respiratory distress, sepsis, hyperbilirubinemia) (62

It helps in replenishing fluids and vitamins quickly rather than the traditional ways that may take several hours

Stockwells lab in Columbia University report that the gene expression of CHAC1, PTGS2, SLC7A11 , and ACSL4 was induced during ferroptosis, and their upregulation detected by qPCR can be regarded as an indicator of ferroptosis (Dixon, Patel et al., 2014, Stockwell, 2022)

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doi: 10.3389/fncel.2019.00212