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Its dysfunctional activation is closely linked to the onset of diseases, particularly inflammation and cancer, making ferroptosis a promising avenue for combating these conditions

Mitochondria can release Ca 2+ into the cytosol via the mitochondrial permeability transition pore (mPTP) or the Na + /Ca 2+ exchanger [23, 24]

J Oncol 2021:112

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Furthermore, they developed adenomyotic lesions that resembled the human disease (Huseby and Thurlow, 1982)