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Protocols are developed under physician guidance and administered by licensed registered nurses (RNs) trained in intravenous therapy and patient monitoring

This type of study in ALS patients has several limitations, including the short life span of the patients, which does not allow following markers of oxidative damage for a long time (longitudinal study), and the impossibility of evaluating oxidative damage markers in early disease, as the initial stage of the disease progresses in a subclinical manner, sometimes years before diagnosis[6]

Comprehensive Recruitment Strategies : Recruiting healthy volunteers requires targeted outreach and effective communication to help confirm that participants meet specific inclusion criteria

are named as co-inventors

Besides the initial design, other factors also need to be considered to maximize prodrug activation