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Cuproptosis: unveiling a new frontier in cancer biology and therapeutics

TNF-, belonging to the Fas family, exhibits a robust interaction with the Fas ligand and triggers caspases, initiating programmed cell death ( Moreover, endothelial and leukocyte cell adhesion molecules like ICAM-1 and VCAM-1 promote the recruitment of leukocytes and immune cells to the site of injury through their interactions with endothelial cells (Frugier et al., 2010)

5.4 Experimental validation of epigenetic mechanisms Recent technological advances in genome editing and single-cell analysis have provided powerful tools to validate EED-induced epigenetic modifications as causal mechanisms underlying transgenerational reproductive toxicity

It serves as the primary line of defense against oxidative stress

USA 105 , 1878218787 (2008) Choo, A