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While standard skin-directed therapies are effective for individuals with indolent early-stage disease, patients with more advanced or refractory forms require systemic treatments, which may consist of chemotherapy, retinoid analogs, interferons, HDAC inhibitors, and antibodies 1,2,3,4

It is currently impossible to study the metabolism of (human) primary auditory cortex in vivo in more spatial detail and thus accessing neurons or neuronal populations specifically involved in tinnitus pathophysiology