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Basically, everything in pool chemistry is impacted by pH in some way or another

The extrinsic pathway involves interaction of cell surface death receptors [for example, Fas/CD95

doi: 10.3390/ijms26168075 45 SharmaAAnandSKSinghNDwivediUNKakkarP

Employing a higher value for the threshold factor k would impose a more stringent selection criterion, preferentially identifying reactions with the strongest linear correlation (R) between flux and predictive contribution