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In some cases, the condition progresses to alopecia totalis (full scalp hair loss) or alopecia universalis (loss of all body hair)

Apalangya V (2024) Potential application of cold plasma technology to control aflatoxin contamination in tropical food product

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This extracellular and mislocalized intracellular copper exacerbates DCM through multiple pathways, activating the TGF-/Smad signaling pathway and amplifying oxidative stress, collectively promoting extracellular matrix deposition and fibrotic remodeling [171]

The decrease in diamine oxidase (DAO) activity would alter histamine metabolism, which could trigger the onset of symptoms due to its accumulation (155)