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In summary, catalpol exhibits clear anti-cancer effects across various human tumor types, including breast, liver, gastric, lung, colorectal cancers, and oral squamous cell carcinoma

Final results of a phase Ib dose-escalation study of PRI-724, a CBP/beta-catenin modulator, plus gemcitabine (GEM) in patients with advanced pancreatic adenocarcinoma (APC) as second-line therapy after FOLFIRINOX or FOLFOX