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Description

We then tested whether other agents that specifically caused nucleotide imbalance (rather than the DNA-driven and RNA-driven effects of 5FU) have the same mechanism of action

Regulation of microglia and macrophage polarization via apoptosis signal-regulating kinase 1 silencing after ischemic/hypoxic injury

doi: 10.1002/cti2.1277 67 ZhangLWZhouPRWeiPCongXWuLLHuaH

Glycolysis and oxidative phosphorylation are primary sources of cellular energy

This includes coordinated effects on both innate and adaptive responses and is mediated by engagement of key inflammatory and antioxidant signaling pathways (Figure 3)