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10.3390/molecules29225364 107 WangX.LiP.JiH.XuZ.XingH

Where appropriate, further investigation, such as testing glutathione status or DHFR genetic variants, may help explain why some individuals respond differently to folic acid and identify when alternative forms of folate may be beneficial

The ATP content in the cell lysate was determined using ATP Bioluminescent cell assay kit according to the manufacturer's suggestion (Sigma, St Louis, MO) and samples were read using the TD-20/20 Luminometer (Turner Designs, Sunnyvale, CA)

However, the research unambiguously shows that dietary supplementation with spermidine, whether through food rich in spermidine or as a pure compound supplementation, mediates health-beneficial effects 9,113

Chen, X.-F., Wang, L., Wu, Y.-Z., Song, S.-Y., Min, H.-Y., & Yang, Y