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And it's all critically important

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Sanajou D, Ghorbani Haghjo A, Argani H, Aslani S (2018) AGE-RAGE axis blockade in diabetic nephropathy: current status and future directions

The dysregulation of gene expression linked to pathological illnesses affecting male reproductive organs, such as spermatogenesis abnormalities and prostate cancers, has been linked to certain subtypes of sncRNAs, especially miRNAs [329, 539]

Moreover, polypeptides of the present invention may be useful in inhibiting the angiogenesis of proliferative cells or tissues, either alone, as a protein fusion, or in combination with other polypeptides directly or indirectly, as described elsewhere herein