glutathione peroxidase enzyme mimetics New mimetics—Insights into antioxidant and cytotoxic activity Glutathione peroxidase-like functions of 1,2-diselenane-4,5-diol

The historically important question, which has been the subject of frequent discussions, is whether oxidative stress is the primary cause or secondary consequence of the disease

Crucially, we integrate the parallel and essential discourse on safety, highlighting how zebrafish models, especially transgenic lines, enable the real-time visualization and mechanistic interrogation of compound-induced hepatotoxicity

doi: 10.1016/S1470-2045(23)00444-8 35 LoMWangYZGoutPW

the yeast strain has a mutation that reduces the ability of the strain to synthesise one or more proteins, metabolites and/or essential growth factors which may optionally be included in the culture medium in limiting amounts, depending on the capacity of the yeast strain to synthesise said proteins, metabolites and/or essential growth factors

(2) induced massive cell death in the highly metastatic human L3.6pl PDAC cells compared to the individual treatment