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Yuan P, Wu WH, Gao L, Zheng ZQ, Liu D, Mei HY, Zhang ZL, Jing ZC

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Additionally, methylation plays a crucial role in epigenetic modifications, which can alter the expression of genes without changing the DNA sequence

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Early work suggested that extracellular NAD + can induce cell death in specific T cell subpopulations, such as nave T cells and regulatory T cells (Tregs), representing the prototype of a new category of danger signals and being known as NAD + -induced cell death (NICD) [100,101,102]