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Non-pharmacological interventions that are standard of care include cognitive and behavioral therapies (CBT) to address issues of anxiety for children with ASD [505, 585] and to promote autonomy and emotional well-being [365]

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5-HMF demonstrated positive correlations with 23 parameters, particularly strong with iditol, imidazopyrimidines, glucose, erythrulose, and C *, while showing negative correlations with carboxylic acids and derivatives, total monosaccharides, and fructose