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Published trials used oral doses of 0.25 mg to 30 mg per day and intravenous single doses of 25 to 400 mcg/kg

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Collectively, this study provides a solid foundation for future exploration into the impact of NNMTi-and diet-mediated changes to the gut microbiome in obese and lean populations, as well as future targets to investigate mechanistically with NNMTi treatment

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