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Together with zinc, they catalyse the rearrangement of dopachrome to 5,6-dihydroxyindole-2-carboxylic acid in the final phase of eumelanin formation in melanogenesis [101, 102]

Genetic testing for cholestasis-related mutations is recommended in paediatric and adult patients if the clinic, biochemistry, and histology suggest cholestasis

In addition, the mean of blood vessel density and the percentage of blood vessel area in tumors were suppressed by 7080%

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Geyikoglu F, Trkez H, Bakir T, Cicek M (2013) The genotoxic, hepatotoxic, nephrotoxic, haematotoxic and histopathological effects in rats after aluminium chronic intoxication