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In-house Human Endogenous Metabolite Compound Library was synthesized by MCE (HY-L030, New Jersey, USA)

Increasing evidence indicates that both AKI and CKD can be ameliorated through several microbiota-directed interventions, including microbial therapeutics (probiotics, prebiotics, and synbiotics), natural products (traditional Chinese medicines (TCM) and natural compounds), and FMT ( Figure 2 and Table 2 ) [81, 84, 173]

In particular, the dietary pattern of the Chinese population, which is characterized by a reduced consumption of fat and calories but an increased intake of dietary fibers, is expected to alter the metabolomic profile of the population, potentially interfering with the progression of MS

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