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doi: 10.1007/s11060-024-04881-2 181 HuangQXuLYeL

Particularly under stress conditions such as hypoxia or nutrient deprivation, this metabolic synergy intensifies, driving tumors to exhibit more aggressive and treatment-resistant phenotypes

b) Apoptosis in Radiation-Induced Digestive Injury Multiple studies have reported the anti-radiation effectiveness of apoptosis-related drugs such as genistein (161), P-glycoprotein (163), sphingosine-1-phosphate (162), ecdysterone combined with paeonol (164), cystine and theanine mixture (153), apocynin (165), dimethyloxallyl glycine (166), deferoxamine (167), 3,3-diindolylmethane (168), hepatocyte growth factor (169), and walnut oligopeptide (170) ( Figure 4 ), indicating that regulating apoptosis may alleviate radiation injury (160)

Goreshnik I

(2024) consistently demonstrated that cynaroside could inhibit NLRP3 inflammasome activation in rats induced by methotrexate