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AD is characterized by the accumulation and aggregation of misfolded proteins in brain, the sustained activation of the UPR mediated by the misfold proteins initiates or mediates neurodegeneration (Hoozemans et al., 2005)

139 , s96s106 (2000)

Summary Cardiac arrhythmia, or abnormal heart rhythm, can lead to ineffective pumping by the heart and, if prolonged and severe, sudden cardiac death (SCD)

Co-supplementation of aged rats with L-carnitine and -lipoic acid blunted age-related increases in reactive oxygen species (ROS), lipid peroxidation, protein carbonylation, and DNA strand breaks in a variety of tissues (heart, skeletal muscle, and brain) (21-30)

Benefici della carnitina nelle donne Il ruolo pi importante della carnitina riguarda il metabolismo dei grassi