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DOI: 10.1172/JCI92390

The major insight from mathematical modeling is this: HcyMetSAMSAH is a cycle , and as such, the Hcy steady state is influenced not only by the Hcy Met flux (including cobalamin) but also entry and exit fluxes of the cycle

Research has demonstrated that the gut microbiome is essential for digestion, metabolism, immune regulation, and neural signaling

Other groups at risk for vitamin B6 deficiency are those who do not consume enough or have increased metabolic requirements, such as people with kidney problems or autoimmune disorders