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It is also believed that the downstream products of these lipid peroxides, like malondialdehyde (MDA) and 4-hydroxy-nonenal (4-HNE), exert ferroptotic damage by degrading proteins or nucleic acids (Liu et al., 2020, 2021)

doi: 10.1016/j.bbrc.2006.05.214 131 HayashiTHoriuchiASanoKHiraokaNKasaiMIchimuraTet al