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Melatonin improves ischemia-induced circulation recovery impairment in mice with streptozotocin-induced diabetes by improving the endothelial progenitor cells functioning

Proteasome activity can be regulated by proteasome quantity and composition, posttranslational modifications and the expression of proteasomal activators [95]

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3 Human -cell lipotoxicity in vitro It is well documented that, upon acute exposure, LC-FFA can promote insulin release from human islets in vitro (55, 56), whilst chronic exposure impairs insulin secretion (5456) and activates apoptosis (5760)

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