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Healthcare system inertia makes systematic changes difficult to implement and sustain

Khavinson V, Evgeny G, Vladimir M, Galina R (2006) Peptide substance stimulating regeneration of central nervous system neurons, pharmaceutical composition on its base, and the method of its application Khavinson V, Diomede F, Mironova E et al (2020) AEDG peptide (epitalon) stimulates gene expression and protein synthesis during neurogenesis: possible epigenetic mechanism

Proc Natl Acad Sci USA 4, 370373 (1918)

(See Table 1 for descriptions of preparation conditions.) In addition to differences in sample collection, processing, and storage methodology, studies also differ in final summary measure reporting

All methods used a Waters ACQUITY ultra-performance liquid chromatography (UPLC) and a Thermo Scientific Q-Exactive high resolution/accurate mass spectrometer interfaced with a heated electrospray ionization (HESI-II) source and Orbitrap mass analyzer operated at 35,000 mass resolution