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The apoptosis attributed to glutamate was preceded by the increase in activator protein-1 (AP-1) caused by the activation of c-Jun N-terminal kinase (JNK) and p38 mitogen-activated protein kinase (MAP kinase) and phosphorylation of c-Jun and p53 129

Integrating BPC-157 with Rehabilitation BPC-157 enhances healing but does not replace proper rehabilitation

(2015) and Campos et al

Lumbar disc degeneration is characterized by disc dehydration, inflammation, extracellular matrix degradation, and cellular senescence, leading to chronic pain and impaired mobility