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It is reported that PGC-1 affects cellular oxidative capacity and fatty acid oxidation through the regulation of mitochondrial and nuclear genes 13,14

The pharmacokinetic advantage is significant: systemic bioavailability of intranasal peptides is typically 1020%, but CNS bioavailability can reach 3060% because the compound travels directly along nerve sheaths into cerebrospinal fluid

The sub/supra-optimal temperature-induced inhibition of photosynthesis and oxidative damage in cucumber leaves are alleviated by grafting onto fig leaf gourd/luffa rootstocks

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Rapamycin, which induces autophagy through the inhibition of mTORC1, and wortmannin, which inhibits autophagy through inhibition of phosphatidylinositol-3-kinase (PI3K), were used as controls (Powis et al., 1994