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The result of this fatty acid accumulation is a sensation of pins and needles or a numbness in the feet and hands

The authors found that a 14 day course of treatment with metronidazole given to healthy dogs, resulted in significant changes in microbiome composition, including severely decreased amounts of a key beneficial bacteria, Fusobacteria

This helps prevent infections and needle blockages

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While water-soluble, vitamin B12 requires the presence of a protein called intrinsic factor (IF) for absorption