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Stored mainly in bone, muscle, and tissues

Evidencing changes indicate the possibility of prebiotics having neuroprotective, stress-buffering effects through the modulation of the MGBA by restoring microbial homeostasis, changing neuroendocrine responses, or affecting gene expression in stress-related brain regions (Burokas et al., 2017)

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As a result, AST-administered rats showed a better survival rate and weight gain in response to necrotizing enterocolitis

Spermine and spermidine mediate protection against oxidative damage caused by hydrogen peroxide