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Int J Mol Med 47(5):19 Shino H, Hasuike A, Arai Y, Honda M, Isokawa K, Sato S (2016) Melatonin enhances vertical bone augmentation in rat calvaria secluded spaces

Ferroptosis is a recently defined programmed cell death, which has been revealed in various organ diseases, such as neurological disorders (16), liver injury (17) and cardiomyopathy (18)

In addition, transgenic mice with cardiac-specific heat shock protein 27 (Hsp27) overexpression developed cardiac hypertrophy and dysfunction, which correlated with increases in GSH levels, GSH/GSSG, and GPx1 activity and with a decrease in total ROS levels in the heart (119)