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As clinical signs of cobalamin deficiency include chronic wasting or failure to thrive, malaise, and gastrointestinal signs such as diarrhea, serum cobalamin concentration should be measured in any dog with poor response to enzyme replacement therapy for EPI

It's typically applied topically to the scalp and does not enter systemic circulation

Open 7 , e2425614 (2024)

Sleep 33, 585592 (2010)

For example, previous research has reported decreases in Atlantic Ocean water salinity with depth, which is opposite of the observed trend in the Pacific 34