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Inter-subject and ethnic differences in paracetamol metabolism

10.16329/j.cnki.zrht.2023.03.006 41 JulianC

A mutant of CEP192 468-533 (Y487A, F490A), in which the two residues that bind the F-pocket were replaced with alanine residues, had a binding affinity of 2 M for Aurora-A CAKD , over 20 times weaker compared to the wild-type CEP192 468-533 (Fig

They concluded, Only BPC 157 was consistently effective in all of the models of acute/chronic injury of the esophagus, stomach, duodenum, and lower gastrointestinal tract