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Mice co-administered sertraline or imipramine with cannabis (20 mg/kg, s.c.) were not statistically different from the vehicle control group as regards their immobility time

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Shank2 knockout mice (e67 KO) exhibit decreased expression levels of Gabra2 and GABA receptor-mediated inhibitory signaling, which can be reversed by treatment with allosteric modulators of GABA-ARs (99, 100)

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