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The copper part isnt a footnote

EMBO J 21, 42294239 (2002)

Induction of various bloodbrain barrier properties in non-neuronal endothelial cells by close apposition to co-cultured astrocytes

J Biol Chem 285:810826

In a recent work, the group of von Zastrow showed that after being recruited by the phosphorylated MOR, arrestin 3 acts as a scaffold, promoting ubiquitination of two lysyl residues in the first intracellular loop by the ubiquitin ligase Smurf2 (Henry et al., DPDPE also enables arrestin-mediated endocytosis of DOR as shown by the partial reduction of internalization when arrestins 2 or 3 are selectively inhibited (Zhang et al., 2005)