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Notably, platelet production follows a circadian rhythm, peaking in the late night and early morning, coinciding with the timing of adverse cardiovascular events ( In epilepsy, administering a higher evening dose of clobazam has been shown to improve seizure control in patients whose seizures occur predominantly at night or in the early morning

Gardner PR, Fridovich I

Decrements in lung function related to arsenic in drinking water in West Bengal, India

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Purity issues, even small ones, can throw off an entire study, so researchers tend to be picky about sourcing for good reason