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For glutathione it is much much more complex

2007, Ko and Fascetti 2016, Donadelli, Pezzali et al

Clin Exp Rheum 41(6):1323-1331, 2023

A decrease in drug metabolism is shown in vapes containing flavouring agents such as benzaldehyde and cinnamaldehyde that are potent inhibitors of the CYP2A6 enzyme, which is primarily responsible for the metabolism of nicotine, leading to an increase in plasma concentration levels of nicotine (Winters et al

Impaired synaptic glutamate clearance may lead to harmful postsynaptic overexcitation, known as excitotoxicity, causing cellular damage and neuronal death (Lewerenz and Maher 2015)