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Johns wort extract, which resulted in lower striatal malondialdehyde levels, increased catalase activity, decreased glutathione (GSH) content, normalized Glial fibrillary acidic protein (GFAP) and tumor necrosis factor alpha or TNF- expression, reduced Deoxyribonucleic acid (DNA) fragmentation, and prevented dopaminergic neuron damage (Kiasalari et al., 2016)

Sestrin2 is induced by glucose starvation via the unfolded protein response and protects cells from noncanonical necroptotic cell death

[DOI] [PMC free article] [PubMed] [Google Scholar] Wang C-C, Peng H, Wang Zet al

This promoted T cell-mediated systemic immunity to exert long-range antitumor effects on tumors and enhance RT efficacy, thereby exhibiting superior antitumor efficacy in a bilateral tumor model and a lung metastatic model of 4T1 breast cancer

Pathogenesis of alcoholic liver disease: Role of oxidative metabolism