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J Proteome Res 2015;14:4050-8

Several transition metal-transporting genes including SLC11A2 (DMT1), TFR2 , SLC25A37 , STEAP1 , MMGT1 and PRNP were identified as robust targets for reduction of Cu toxicity (Fig

This occurs because the senescence of hepatic stellate cells, which are partly responsible for forming fibrotic scar tissue, acts as a natural mechanism that delays and limits fibrotic changes in response to injury [142, 143]

10.1038/srep12936 225 ZhouF.ZhuZ.GaoJ.YangC.WenL.LiuL.et al (2018)

While human clinical data on GHK-Cu's cognitive effects is still sparse, the current evidence and the compound's known influence on gene expression networks involved in neuronal survival are noteworthy