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The Mechanistic Case for Stacking Tirzepatide and 5-Amino-1MQ Tirzepatide functions as a dual GIP (glucose-dependent insulinotropic polypeptide) and GLP-1 (glucagon-like peptide-1) receptor agonist

This capability enhances therapeutic precision while minimizing side effects and limiting resistance development

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In addition, we demonstrated that the iron chelator CPX rescues ferroptotic cell death under cystine deprivation conditions (Extended Data Fig