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Evidence-Based Nutritional Interventions Lutein and Zeaxanthin: Macular Pigment Optimization Lutein and zeaxanthin are hydroxylated carotenoids that selectively accumulate in the macula, forming the macular pigment optical density (MPOD)

(A) Aggregated results of 49 murine scRNAseq datasets showing expression of genes for canonical melatonin receptors, melatonin synthesis, and the NRF2-Glutathione pathway

Sampson et al., 2020)

Lastly, IF is not recommended for individuals with significant hormonal imbalances, pregnant and breastfeeding women, children, older adults, individuals with an active or previous eating disorder, and those with a compromised immune system