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*Correspondence: Chuan Xiang, [email protected] These authors have contributed equally to this work Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers

Cells depleted of B12 showed impaired ability to carry out efficient energy conversion at the mitochondrial level

The time of day is inconsequentail consistency is far more important

It may support: Cartilage regeneration Joint inflammation reduction Pain relief during physical activity This makes it a compelling option for individuals with joint pain or conditions like osteoarthritis, improving both mobility and exercise sustainability 2

One first treatment option is to consider Physical Therapy