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Up-regulation of matrix metalloproteinase-3 in the dorsal root ganglion of rats with paclitaxel-induced neuropathy

e-mail: [email protected] This article was submitted to Frontiers in Experimental Pharmacology and Drug Discovery, a specialty of Frontiers in Pharmacology

While the functions of the HEAT-repeats are relatively well-understood 21 , the roles of the IDR, due to its structural flexibility, which prevents its visualization in cryo-EM structures, remains largely unclear 20