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10.1126/science.1221592 Science 67 PandaS.AntochM.MillerB

Crain, B

In fact, melatonin ameliorated the antioxidant defenses of the animals by improving the Nrf2 and BNDF expression

The approval is backed by data from the pivotal Phase III PERSEUS study, where treatment with subcutaneous Darzalex Faspro reduced the risk of disease progression or death by 60% in the intended patient population compared to standard of care