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When the cells cannot produce energy efficiently and the blood vessels remain in a state of chronic inflammation, the entire body suffers

doi: 10.1186/s13568-017-0326-0

Several of these copperbinding motifs catalyze formation of reactive oxygen species (ROS), which is believed to be involved in these proteins role in neurodegenerative disorders

I.KhanN.RizwanM.AliS.AhmadA.et al

As mentioned earlier, Bax and BCL-2 play an opposite role in the regulation of apoptosis and thus the ratio of Bax to BCL-2 is often used as an indicator for apoptosis