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Relying solely on food sources may limit the potential for significant increases in glutathione levels

Heavy metals can also replace metallic cofactors in key enzymes, perturbing metabolic reactions and inducing excessive ROS production, thereby amplifying oxidative stress (Fig

Nicotine increased concentrations of thiobarbituric acid, conjugated dienes, and hydroperoxides in the tissues

This was achieved by constraining tail movements driven by muscles and providing feedback directly to motor neuron spikes in the spinal cord

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