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Ketogenic diet consumption inhibited mitochondrial one-carbon metabolism

Park J, Choi J, Cho I, Sheen YY (2022) Radiotherapy-induced oxidative stress and fibrosis in breast cancer are suppressed by vactosertib, a novel, orally bioavailable TGF-/ALK5 inhibitor

Mechanistically, elevated lactate in mouse myocardial tissue and HUVECs triggers Snail1 lactylation, activating the TGF-/Smad2 signaling pathway and eventually promoting EndMT and cardiac dysfunction

Oxidants, oxidative stress and the biology of ageing

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