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In mice, supplementation with auraptene (P45-60) and umbelliprennin in males (for 7 days between P51-60) [62] prevented POS-induced anxiety-like behavior in OFT and EPM at two months of age [63] and in the EPM immediately after treatment [62]

7DK) These results provide evidence that necroptosis, specifically through STK38-mediated RIPK1 activation, constitutes a critical tumour-suppressive mechanism in CRC