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Treatment options include: Praziquantel cream Pimecrolimus cream Antibiotic creams Oral vitamin A analogs Oral antibiotics Non-steroidal anti-inflammatory drugs (NSAIDs) Avoid the use of cosmetics, cleansers, and moisturizers during the treatment Avoid strenuous physical exercise until the skin heals Does perioral dermatitis go away on its own

However, if you are ill, high doses of vitamin B12 that you might receive to treat a deficiency may cause some symptoms, such as: What to avoid while taking B12

It is not listed on the 503B compounding bulk substances list (per FDA Warning Letter, Jan 2026)

Cyanocobalamin can also be prescribed to treat pernicious anemia, a condition where the body is unable to absorb sufficient amounts of vitamin B12 from food