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We assessed the effects of the drugs on the physiological status of diabetic mice by measuring blood glucose, body weight, and cell counts in several organs, as well as effects of thymulin and PRDX6 on the immune status of diabetic mice measuring concentrations of pro-inflammatory cytokines in blood plasma (TNF-, interleukin-5 and 17, and interferon-), activity of NF-B and JNK pathways, and Hsp90 expression in immune cells

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These types of models are commonly used to investigate how signaling molecules influence coordinated repair responses rather than isolated cellular processes

Vilon (also Lys-Glu) is one of the shortest bioregulators in the lineup, studied for similar immune-restoration effects and biological-age markers in rodent models

Other tests, including serum protein electrophoresis (SPEP), hepatitis serologies, and HIV tests, were negative